Characterization of Novel Microelectrode Geometries for Detection of Neurotransmitters

Author

Pettine, Warren ; Jibson, Matthew ; Chen, Tom ; Tobet, Stuart ; Nikkel, Phil ; Henry, Charles S.

Author_Institution

Colorado State Univ., Fort Collins, CO, USA

Volume

12

Issue

5

fYear

2012

fDate

5/1/2012 12:00:00 AM

Firstpage

1187

Lastpage

1192

Abstract

In this paper, a microelectrode array is introduced and characterized using differential pulse voltammetry (DPV), amperometry and fast scan cyclic voltammetry with norepinephrine as a model neurotransmitter. Twenty-one sensor geometries were evaluated with DPV to determine optimal electrode configurations. Next, electrode responses were characterized for the best electrode geometry using an onboard platinum pseudo-reference electrode, whose reliability is established.

Keywords

amperometric sensors; electrochemical electrodes; microelectrodes; neurophysiology; voltammetry (chemical analysis); DPV; amperometry; cyclic voltammetry; differential pulse voltammetry; electrode geometry; electrode response; microelectrode array; microelectrode geometry; neurotransmitter detection; norepinephrine; onboard platinum pseudoreference electrode; optimal electrode configuration; reliability; Arrays; Electric potential; Geometry; Microelectrodes; Neurotransmitters; Platinum; Amperometry; differential pulse voltammetry; fast scan cyclic voltammetry; microelectrode array; norepinephrine; platinum pseudo-reference electrode;

fLanguage

English

Journal_Title

Sensors Journal, IEEE

Publisher

ieee

ISSN

1530-437X

Type

jour

DOI

10.1109/JSEN.2011.2163708

Filename

5976363