Title :
Microwave tomography: two-dimensional system for biological imaging
Author :
Semenov, Serguei Y. ; Svenson, Robert H. ; Boulyshev, Alexander E. ; Souvorov, Alexander E. ; Borisov, Vladimir Y. ; Sizov, Yuri ; Starostin, Andrey N. ; Dezern, Kathy R. ; Tatsis, George P. ; Baranov, Vladimir Y.
Author_Institution :
Lab. of Laser & Appl. Technol., Carolinas Heart Inst., Charlotte, NC, USA
Abstract :
Microwave tomographic imaging is one of the new technologies which has the potential for important applications in medicine. Microwave tomographically reconstructed images may potentially provide information about the physiological state of tissue as well as the anatomical structure of an organ. A two-dimensional (2-D) prototype of a quasi real-time microwave tomographic system was constructed. It was utilized to reconstruct images of physiologically active biological tissues such as an explanted canine perfused heart. The tomographic system consisted of 64 special antennae, divided into 32 emitters and 32 receivers which were electronically scanned. The cylindrical microwave chamber had an internal diameter of 360 mm and was filled with various solutions, including deionized water. The system operated on a frequency of 2.45 GHz. The polarization of the incident electromagnetic field was linear in the vertical direction. Total acquisition time was less than 500 ms. Both accurate and approximation methods of image reconstruction were used. Images of 2-D phantoms, canine hearts, and beating canine hearts have been achieved. In the worst-case situation when the 2-D diffraction model was used for an attempt to "slice" three-dimensional (3-D) object reconstruction, the authors still achieved spatial resolution of 1 to 2 cm and contrast resolution of 5%.
Keywords :
computerised tomography; image reconstruction; medical image processing; microwave imaging; 2-D diffraction model; 2-D phantoms; 2.45 GHz; 360 mm; 500 ms; acquisition time; antennae; biological imaging; cylindrical microwave chamber; deionized water; electromagnetic field polarization; emitters; explanted canine perfused heart; microwave tomography; physiologically active biological tissues; receivers; spatial resolution; two-dimensional system; Anatomical structure; Biomedical imaging; Heart; Image reconstruction; Microwave imaging; Microwave technology; Prototypes; Spatial resolution; Tomography; Two dimensional displays; Animals; Dogs; Heart; Image Processing, Computer-Assisted; Microwaves; Models, Cardiovascular; Phantoms, Imaging; Sensitivity and Specificity; Tomography;
Journal_Title :
Biomedical Engineering, IEEE Transactions on