DocumentCode :
1294423
Title :
Potential distribution for a spheroidal cell having a conductive membrane in an electric field
Author :
Jerry, Rocco A. ; Popel, Aleksander S. ; Brownell, William E.
Author_Institution :
Dept. of Biomed. Eng., Johns Hopkins Univ. Sch. of Med., Baltimore, MD, USA
Volume :
43
Issue :
9
fYear :
1996
Firstpage :
970
Lastpage :
972
Abstract :
When a cell is situated in a uniform electric field, the field is modified due to the relatively low conductance of the cell membrane compared to that of the surrounding fluids. In certain cases, such as in the estimation of internal and external electrokinetic forces, one requires a means of estimating the magnitude of the electric field inside and outside the cell. Most treatments consider the case when the membrane has zero conductivity, or the case of only a spherical cell. The authors solve Laplace´s equation for the electric potential distribution inside and outside a cell having a prolate spheroidal shape and having a membrane with a finite, nonzero conductivity.
Keywords :
Laplace equations; bioelectric potentials; biomembranes; cellular biophysics; voltage distribution; Laplace´s equation; conductive membrane; external electrokinetic forces; internal electrokinetic forces; prolate spheroidal shape; spheroidal cell potential distribution; uniform electric field; zero conductivity membrane; Auditory system; Biomedical engineering; Biomembranes; Cells (biology); Conductivity; Electric potential; Laplace equations; Neck; Shape; Surgery; Cell Membrane; Cell Physiology; Electric Conductivity; Electromagnetic Fields; Ion Channels; Models, Biological; Surface Properties;
fLanguage :
English
Journal_Title :
Biomedical Engineering, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9294
Type :
jour
DOI :
10.1109/10.532132
Filename :
532132
Link To Document :
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