Estimation method using modified Q-Q probability plot in high-frequency ultrasound

By using two different analysis method, the scatter structure of rat liver was evaluated. Rat liver of fibrosis, NASH and control model were prepared. The self-made scanner system with 15-MHz ultrasound, which has good spatial resolution compared with commercial ultrasound scanner, were constructed. The single focused transducer with 15-MHz resonant frequency and 200μm lateral resolution was employed for the measurement. To quantitatively evaluate the scatter structure, two parameters were evaluated: the quantile-quantile (Q-Q) parameter and the scatterer size. As a result, there was no significant difference between the three different rat models.