• DocumentCode
    1306344
  • Title

    Engineering the Human Genome Project

  • Author

    Beugelsdijk, Tony J.

  • Author_Institution
    Los Alamos Nat. Lab., NM, USA
  • Volume
    9
  • Issue
    4
  • fYear
    1990
  • Firstpage
    34
  • Lastpage
    38
  • Abstract
    The Human Genome Initiative, a worldwide research effort to analyze the structure of human deoxyribonucleic acid (DNA) and determine the location of all human genes, is discussed. The nature of the task is described, and the technologies needed to construct ´libraries´ of overlapping clones of DNA fragments are examined. DNA sequencing methods and technologies are also discussed. The role that the engineer could play in supporting the project by advances in instrumentation is briefly discussed.<>
  • Keywords
    DNA; biological techniques and instruments; molecular biophysics; DNA; Human Genome Initiative; genes; human deoxyribonucleic acid; instrumentation; molecular biophysics; overlapping clones; research; sequencing methods; Biochemistry; Bioinformatics; Biological cells; Cells (biology); Cloning; DNA; Genomics; Humans; Libraries; Sequences;
  • fLanguage
    English
  • Journal_Title
    Potentials, IEEE
  • Publisher
    ieee
  • ISSN
    0278-6648
  • Type

    jour

  • DOI
    10.1109/45.65867
  • Filename
    65867