Title :
Multifunctional Ferromagnetic Disks for Modulating Cell Function
Author :
Vitol, Elina A. ; Novosad, Valentyn ; Rozhkova, Elena A.
Author_Institution :
Mater. Sci. Div., Argonne Nat. Lab., Argonne, IL, USA
Abstract :
In this work, we focus on the methods for controlling cell function with ferromagnetic disk-shaped particles. We will first review the history of magnetically assisted modulation of cell behavior and applications of magnetic particles for studying physical properties of a cell. Then, we consider the biological applications of the microdisks such as the method for induction of cancer cell apoptosis, controlled drug release, hyperthermia and MRI imaging.
Keywords :
biomedical MRI; cancer; cellular biophysics; discs (structures); drugs; ferromagnetic materials; history; hyperthermia; magnetic particles; patient treatment; MRI imaging; biological applications; cancer cell apoptosis; cell behavior; cell function modulation; drug release; ferromagnetic disk-shaped particles; history; hyperthermia; magnetic particle applications; magnetically assisted modulation; microdisks; multifunctional ferromagnetic disks; physical properties; Biomembranes; Calcium; Drugs; Iron; Magnetic particles; Magnetic resonance imaging; Magnetomechanical effects; Biomagnetics; MRI; ferromagnetic disks; hyperthermia; magnetomechanical cell actuation;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2012.2198209
