Robust control of blood gases during extracorporeal circulation

This study considers the problem of controlling the patient blood gases with the objective of maintaining these blood gases in their physiological ranges during a stable extracorporeal circulation process. It focuses on regulating the arterial partial pressure of oxygen and carbon dioxide. Two distinct control design schemes are considered. The first scheme is based on H₂ performance and the second scheme is derived from an H_∞ criteria. By incorporating a general dynamic output-feedback controller, LMI-based characterisation of the controller design are established. Using typical case studies, simulation experiments are performed and the ensuing results are analysed and compared.