• DocumentCode
    1332158
  • Title

    Efficient Molecular Imaging Techniques Using Optically Active Molecules

  • Author

    Giakos, G.C. ; Paturi, S. Atreya ; Valluru, K. ; Bathini, P. ; Adya, V. ; Sukumar, S. ; Ambadipudi, K. ; Mandadi, B. ; Becker, M. ; Athawale, S. ; Farajipour, P. ; Marotta, S. ; Sheffer, D. ; Livanos, George ; Zervakis, Michael

  • Author_Institution
    Dept. of Electr. & Comput. Eng., Univ. of Akron, Akron, OH, USA
  • Volume
    59
  • Issue
    11
  • fYear
    2010
  • Firstpage
    2877
  • Lastpage
    2886
  • Abstract
    Efficient imaging techniques aimed at the increasing of the image contrast of a structure, surrounded by a scattering medium, using optically active and high index of refraction molecules as molecular contrast agents, are presented. Specifically, an enhanced degree of linear polarization (DOLP) target detection and imaging is obtained by doping the surrounding medium with molecular contrast agents consisting of aqueous glucose, aqueous alcohol, and salt molecules, in conjunction with advanced polarimetric imaging techniques. The outcome of this paper opens new horizons in the areas of imaging, with emphasis on medical arena, industry, and detection technology.
  • Keywords
    biomedical optical imaging; polarimetry; refractive index; DOLP; advanced polarimetric imaging; aqueous alcohol; aqueous glucose; image contrast; linear polarization; molecular contrast agents; molecular imaging; optically active molecules; refractive index; salt molecules; target detection; Biomedical optical imaging; Optical imaging; Optical polarization; Optical refraction; Optical scattering; Optical sensors; Enhanced degree of linear polarization (DOLP); Stokes´ parameters imaging; enhanced DOLP image contrast resolution; high index of refraction molecules; molecular imaging using optically active molecules;
  • fLanguage
    English
  • Journal_Title
    Instrumentation and Measurement, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9456
  • Type

    jour

  • DOI
    10.1109/TIM.2010.2045538
  • Filename
    5582281