Title :
The importance of pulsatile microcirculation in relation to hypertension
Author :
Jan, Min-Yie ; Hsin Hsiu ; Hsu, Tse-Lin ; Wang, Yuh-Lin ; Wang, Wei-Kung
Author_Institution :
Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei, Taiwan
Abstract :
The aim of the study presented was to prove that increased pulsatile blood pressure (PBP) increases perfusion in peripheral vascular beds (PVBs). We used a laser Doppler flowmeter (LDF) to measure surface renal cortical flux (RCF) and a pressure-tip transducer catheter to measure abdominal aortic blood pressure (AABP). Besides demonstrating the relationship between RCF and AABP by linear regressive analysis with an averaged periodogram (AP), we also used time-domain pulse averaging to clarify the pulsatile AABP and RCF. Furthermore, we define a flux-to-pressure-area ratio (FPAR) to evaluate the efficiency by which the pulsatile AABP drives RCF
Keywords :
blood vessels; diseases; haemodynamics; haemorheology; kidney; medical signal processing; pulsatile flow; statistical analysis; abdominal aortic blood pressure; averaged periodogram; efficiency; flux-to-pressure-area ratio; hypertension; increased pulsatile blood pressure; laser Doppler flowmeter; linear regressive analysis; perfusion; peripheral vascular beds; pressure-tip transducer catheter; pulsatile microcirculation; surface renal cortical flux; time-domain pulse averaging; Abdomen; Arteriosclerosis; Blood flow; Blood pressure; Cardiac disease; Cardiovascular diseases; Heart; Hypertension; Physics; Pressure measurement;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE