DocumentCode :
1345847
Title :
Image reconstruction in intravascular photoacoustic imaging
Author :
Sheu, Yae-Lin ; Chou, Cheng-Ying ; Hsieh, Bao-Yu ; Li, Pai-Chi
Author_Institution :
Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei, Taiwan
Volume :
58
Issue :
10
fYear :
2011
fDate :
10/1/2011 12:00:00 AM
Firstpage :
2067
Lastpage :
2077
Abstract :
Intravascular photoacoustic (IVPA) imaging is a technique for visualizing atherosclerotic plaques with differential composition. Unlike conventional photoacoustic tomography scanning, where the scanning device rotates around the subject, the scanning aperture in IVPA imaging is enclosed within the imaged object. The display of the intravascular structure is typically obtained by converting detected photoacoustic waves into Cartesian coordinates, which can produce images with severe artifacts. Because the acquired data are highly limited, there does not exist a stable reconstruction algorithm for such imaging geometry. The purpose of this work was to apply image reconstruction concepts to explore the feasibility and efficacy of image reconstruction algorithms in IVPA imaging using traditional analytical formulas, such as a filtered back-projection (FBP) and the lambda-tomography method. Although the closed-form formulas are not exact for the IVPA system, a general picture of and interface information about objects are provided. To improve the quality of the reconstructed image, the iterative expectation maximization and penalized least-squares methods were adopted to minimize the difference between the measured signals and those generated by a reconstructed image. In this work, we considered both the ideal point detector and the acoustic transducers with finite- size aperture. The transducer effects including the spatial response of aperture and acoustoelectrical impulse responses were incorporated in the system matrix to reduce the aroused distortion in the IVPA reconstruction. Computer simulations and experiments were carried out to validate the methods. The applicability and the limitation of the reconstruction method were also discussed.
Keywords :
acoustic tomography; acoustic transducers; acoustoelectric effects; biomedical optical imaging; biomedical transducers; biomedical ultrasonics; blood vessels; diseases; expectation-maximisation algorithm; image reconstruction; least squares approximations; medical image processing; optical tomography; photoacoustic effect; Cartesian coordinate; acoustic transducer; acoustoelectrical impulse response; atherosclerotic plaque; filtered back projection; finite size aperture; ideal point detector; image reconstruction algorithm; imaging geometry; intravascular photoacoustic imaging; iterative expectation maximization; lambda tomography; penalized least squares method; photoacoustic tomography scanning; photoacoustic wave; Apertures; Catheters; Detectors; Geometry; Image reconstruction; Imaging; Transforms; Algorithms; Artifacts; Computer Simulation; Hair; Humans; Image Processing, Computer-Assisted; Least-Squares Analysis; Models, Biological; Phantoms, Imaging; Photoacoustic Techniques; Reproducibility of Results; Signal Processing, Computer-Assisted; Transducers; Ultrasonography, Interventional;
fLanguage :
English
Journal_Title :
Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on
Publisher :
ieee
ISSN :
0885-3010
Type :
jour
DOI :
10.1109/TUFFC.2011.2057
Filename :
6039997
Link To Document :
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