Title :
Multiobjective Optimization of an Electrostimulative Acetabular Revision System
Author :
Potratz, Carsten ; Kluess, Daniel ; Ewald, Hartmut ; Van Rienen, Ursula
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Rostock, Rostock, Germany
Abstract :
In this paper, we present a new approach for the enhancement of the bone proliferation rate by electrostimulation in the acetabular region. Based on the complex tissue structure in this area, the electric field distributions were computed by numerical means using a model based on high-resolution computed tomography scans of the acetabular area. This results in a complex, nonlinear, and discrete optimization problem. Therefore, an adapted algorithm was developed to reduce the computational effort in the order of several magnitudes. We divided the procedure into two stages: data extraction and a subsequent optimization process. The used optimization algorithm utilizes an evolutionary concept and a multidimensional definition of optimality for different, partly contradictive objective functions. Finally, we present first optimization results for different stimulation situations.
Keywords :
bioelectric phenomena; bone; computerised tomography; optimisation; physiological models; prosthetics; acetabular region; bone proliferation; complex optimization problem; complex tissue structure; data extraction; discrete optimization problem; electric field distributions; electrostimulation; electrostimulative acetabular revision system; endoprosthesis; high-resolution computed tomography; layered bone model; multidimensional optimality definition; multiobjective optimization; nonlinear optimization problem; partly contradictive objective functions; Bones; Coils; Couplings; Data mining; Delay; Distributed computing; Electrodes; Electromagnetic fields; Frequency; Medical treatment; Multidimensional systems; Surgery; Electrostimulation; Pareto; multidimensional; optimization; simulation; Acetabulum; Algorithms; Bone Regeneration; Computer Simulation; Electric Stimulation Therapy; Electrodes, Implanted; Guided Tissue Regeneration; Hip Prosthesis; Humans; Models, Biological; Nonlinear Dynamics; Prosthesis Design;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2009.2030961