DocumentCode
1365497
Title
Interactive Virtual Probing of 4D MRI Blood-Flow
Author
Van Pelt, Roy ; Bescós, Javier Oliván ; Breeuwer, Marcel ; Clough, Rachel E. ; Gröller, M. Eduard ; ter Haar Romeny, Bart ; Vilanova, Anna
Author_Institution
Dept. of Biomed. Eng., Eindhoven Univ. of Technol., Eindhoven, Netherlands
Volume
17
Issue
12
fYear
2011
Firstpage
2153
Lastpage
2162
Abstract
Better understanding of hemodynamics conceivably leads to improved diagnosis and prognosis of cardiovascular diseases. Therefore, an elaborate analysis of the blood-flow in heart and thoracic arteries is essential. Contemporary MRI techniques enable acquisition of quantitative time-resolved flow information, resulting in 4D velocity fields that capture the blood-flow behavior. Visual exploration of these fields provides comprehensive insight into the unsteady blood-flow behavior, and precedes a quantitative analysis of additional blood-flow parameters. The complete inspection requires accurate segmentation of anatomical structures, encompassing a time-consuming and hard-to-automate process, especially for malformed morphologies. We present a way to avoid the laborious segmentation process in case of qualitative inspection, by introducing an interactive virtual probe. This probe is positioned semi-automatically within the blood-flow field, and serves as a navigational object for visual exploration. The difficult task of determining position and orientation along the view-direction is automated by a fitting approach, aligning the probe with the orientations of the velocity field. The aligned probe provides an interactive seeding basis for various flow visualization approaches. We demonstrate illustration-inspired particles, integral lines and integral surfaces, conveying distinct characteristics of the unsteady blood-flow. Lastly, we present the results of an evaluation with domain experts, valuing the practical use of our probe and flow visualization techniques.
Keywords
biomedical MRI; blood; blood vessels; data visualisation; flow instability; flow visualisation; haemodynamics; virtual reality; 4D MRI blood-flow behaviour; 4D velocity field; anatomical structure; anatomical structure segmentation; blood-flow parameter; cardiovascular disease; flow visualization approach; hard-to-automate process; hemodynamics; interactive virtual probing; laborious segmentation process; malformed morphology; object navigation; thoracic artery; time-resolved flow information; visual exploration; Blood flow; Data visualization; Magnetic resonance imaging; Three dimensional displays; Flow visualization; Illustrative visualization; Multivalued images; Phase-contrast cine MRI.; Probing; Blood Flow Velocity; Cardiovascular Diseases; Computer Graphics; Computer Simulation; Hemodynamics; Humans; Imaging, Three-Dimensional; Magnetic Resonance Angiography; User-Computer Interface;
fLanguage
English
Journal_Title
Visualization and Computer Graphics, IEEE Transactions on
Publisher
ieee
ISSN
1077-2626
Type
jour
DOI
10.1109/TVCG.2011.215
Filename
6064980
Link To Document