DocumentCode :
1368237
Title :
A Novel Cell Irradiation System Using 90 ^{\\circ} -Scattering Technique
Author :
Cho, I.C. ; Weng, M.F. ; Wu, J.M. ; Chiang, S.Y. ; Chou, W.T. ; Niu, H. ; Hsu, C.-H.
Author_Institution :
Dept. of Biomed. Eng. & Environ. Sci., Nat. Tsing Hua Univ., Hsinchu, Taiwan
Volume :
58
Issue :
1
fYear :
2011
Firstpage :
95
Lastpage :
98
Abstract :
A novel cell irradiation system was developed for use with the HVEE Van de Graaff accelerator at the National Tsing Hua University. A 90°-scattering technique using an Au foil was designed, in which charged particles were directed from horizontal to vertical irradiation. Beam performance was tested with a silicon detector and a CR-39 nuclear track detector. The HeLa cells were irradiated with 2-MeV alpha particles and the formation of giant cells was observed. The result showed that this system provides a convenient way of generating a vertical particle beam and a cell-supporting chamber, thereby allowing a suitable cell growth condition during irradiation. Furthermore, establishment of such a system is more convenient and economical than the alternatives.
Keywords :
alpha-particle effects; biological effects of radiation; ion beam applications; position sensitive particle detectors; silicon radiation detectors; van de Graaff accelerators; 90°-scattering technique; Au foil; CR-39 nuclear track detector; HVEE Van de Graaff accelerator; HeLa cells; alpha particles; cell growth; cell irradiation system; cell-supporting chamber; charged particles; electron volt energy 2 MeV; giant cells; ion beam applications; silicon detector; vertical particle beam; Accelerator; biological effect of radiation; ion beam applications;
fLanguage :
English
Journal_Title :
Nuclear Science, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9499
Type :
jour
DOI :
10.1109/TNS.2010.2087036
Filename :
5618602
Link To Document :
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