Editorial: What Biomedical Engineers Can Do to Impact Multiscale Modeling (TBME Letters Special Issue on Multiscale Modeling and Analysis in Computational Biology and Medicine: Part-2)

In virtually every scientific endeavor, computational models are used to aid the design and predict aspects of the physical world around us. Engineers see modeling as a necessary tool for developing research questions and designing tools. In biology and medicine, scientists have long used conceptual models to explain relatively uncomplicated data, and increasingly com putational models are recognized as an important platform for discovery and translation of complex data. We cannot, however, ignore the large number of skeptics who often question the use fulness of biocomputational models, as their ultimate impact is still debatable.