DocumentCode :
1382296
Title :
Learning an L1-Regularized Gaussian Bayesian Network in the Equivalence Class Space
Author :
Vidaurre, Diego ; Bielza, Concha ; Larranaga, Pedro
Author_Institution :
Dept. de Intel. Artificial, Univ. Politec. de Madrid, Madrid, Spain
Volume :
40
Issue :
5
fYear :
2010
Firstpage :
1231
Lastpage :
1242
Abstract :
Learning the structure of a graphical model from data is a common task in a wide range of practical applications. In this paper, we focus on Gaussian Bayesian networks, i.e., on continuous data and directed acyclic graphs with a joint probability density of all variables given by a Gaussian. We propose to work in an equivalence class search space, specifically using the k-greedy equivalence search algorithm. This, combined with regularization techniques to guide the structure search, can learn sparse networks close to the one that generated the data. We provide results on some synthetic networks and on modeling the gene network of the two biological pathways regulating the biosynthesis of isoprenoids for the Arabidopsis thaliana plant.
Keywords :
Gaussian processes; belief networks; directed graphs; greedy algorithms; learning (artificial intelligence); probability; Arabidopsis thaliana plant; L1-regularized Gaussian Bayesian network; biological pathways; continuous data; directed acyclic graphs; equivalence class search space; equivalence class space; graphical model; isoprenoids biosynthesis; joint probability density; k-greedy equivalence search algorithm; regularization techniques; Bayesian methods; Biological information theory; Biological system modeling; Boolean functions; Covariance matrix; Data structures; Graphical models; Induction generators; Plants (biology); Random variables; $k$-greedy equivalence search (GES); Equivalence class; Lasso; gene networks; graphical Gaussian model; microarrays; network induction; regularization; Algorithms; Arabidopsis; Bayes Theorem; Computer Simulation; Gene Expression Regulation; Models, Biological; Models, Statistical; Normal Distribution; Plant Proteins; Signal Transduction; Terpenes;
fLanguage :
English
Journal_Title :
Systems, Man, and Cybernetics, Part B: Cybernetics, IEEE Transactions on
Publisher :
ieee
ISSN :
1083-4419
Type :
jour
DOI :
10.1109/TSMCB.2009.2036593
Filename :
5382574
Link To Document :
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