Title :
A mathematical model for the assessment of hemodynamic parameters using quantitative contrast echocardiography
Author :
Chen, Xucai ; Schwarz, Karl Q. ; Phillips, Daniel ; Steinmetz, Sherry D. ; Schlief, Reinhard
Author_Institution :
Dept. of Med., Rochester Univ., NY, USA
fDate :
6/1/1998 12:00:00 AM
Abstract :
A mathematical model for the assessment of hemodynamic parameters using quantitative echocardiography is presented. The method involves the intravenous injection of an ultrasonic echo contrast agent. The relative enhancement of the backscattered ultrasound intensity is measured as a function of time (the time-intensity curve). From this measurement, the volume flow rate (cardiac output) and the mixing volume are calculated. Relevant acoustic properties of the ultrasound contrast agent are discussed. An in vitro experiment is performed to corroborate the theory presented.
Keywords :
backscatter; echocardiography; haemodynamics; physiological models; acoustic properties; backscattered ultrasound intensity relative enhancement; cardiac output; hemodynamic parameters assessment; in vitro experiment; intravenous injection; mathematical model; medical diagnostic imaging; mixing volume; quantitative contrast echocardiography; time-intensity curve; ultrasonic echo contrast agent; ultrasound contrast agent; volume flow rate; Acoustic measurements; Echocardiography; Fluid flow measurement; Hemodynamics; In vitro; Mathematical model; Time measurement; Ultrasonic imaging; Ultrasonic variables measurement; Volume measurement; Calibration; Contrast Media; Echocardiography; Hemodynamics; Humans; Image Enhancement; Models, Cardiovascular; Nonlinear Dynamics; Phantoms, Imaging; Reproducibility of Results;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
