Title :
An integrated PET-SPECT small animal imager: preliminary results
Author :
Del Guerra, A. ; Damiani, C. ; Di Domenico, G. ; Motta, A. ; Giganti, M. ; Marchesini, R. ; Piffanelli, A. ; Sabba, N. ; Sartori, L. ; Zavattini, G.
Author_Institution :
Dipt. di Fisica, Pisa Univ., Italy
fDate :
8/1/2000 12:00:00 AM
Abstract :
The authors have successfully built and characterised a small animal PET based on 4 rotating detectors with a spatial resolution <2 mm over its field of view and a sensitivity of 640 cps/μCi at the centre. The scanner is based on four matrices of 400 YAP:Ce finger crystals (2×2×30 mm3 each) coupled to Position Sensitive PhotoMultipliers (Hamamatsu R2486-06.) The authors have now applied two high resolution collimators to two opposite detectors, hence realising an integrated PET-SPECT scanner for small animals. The collimators are made of lead with 20 mm long, 0.6 mm hexagonal holes with 0.15 mm septa. The read-out and data acquisition system are handled by NIM-CAMAC standard electronics. The Field Of View (FOV) of the tomograph has a diameter of 4 cm and an axial length of 4 cm in both PET and SPECT configuration which is appropriate for mice and rat studies
Keywords :
biological techniques; data acquisition; image resolution; photomultipliers; positron emission tomography; single photon emission computed tomography; 0.15 mm to 4 cm; NIM-CAMAC standard electronics; Pb; YAP:Ce; YAlO3:Ce; integrated PET-SPECT small animal imager; lead collimators; mice studies; position sensitive photomultipliers; rat studies; read-out; rotating detectors; spatial resolution; Animals; Collimators; Crystals; Data acquisition; Fingers; Mice; Photomultipliers; Position sensitive particle detectors; Positron emission tomography; Spatial resolution;
Journal_Title :
Nuclear Science, IEEE Transactions on
