An integrated PET-SPECT small animal imager: preliminary results

Author

Del Guerra, A. ; Damiani, C. ; Di Domenico, G. ; Motta, A. ; Giganti, M. ; Marchesini, R. ; Piffanelli, A. ; Sabba, N. ; Sartori, L. ; Zavattini, G.

Author_Institution

Dipt. di Fisica, Pisa Univ., Italy

Volume

47

Issue

4

fYear

2000

fDate

8/1/2000 12:00:00 AM

Firstpage

1537

Lastpage

1540

Abstract

The authors have successfully built and characterised a small animal PET based on 4 rotating detectors with a spatial resolution <2 mm over its field of view and a sensitivity of 640 cps/μCi at the centre. The scanner is based on four matrices of 400 YAP:Ce finger crystals (2×2×30 mm³ each) coupled to Position Sensitive PhotoMultipliers (Hamamatsu R2486-06.) The authors have now applied two high resolution collimators to two opposite detectors, hence realising an integrated PET-SPECT scanner for small animals. The collimators are made of lead with 20 mm long, 0.6 mm hexagonal holes with 0.15 mm septa. The read-out and data acquisition system are handled by NIM-CAMAC standard electronics. The Field Of View (FOV) of the tomograph has a diameter of 4 cm and an axial length of 4 cm in both PET and SPECT configuration which is appropriate for mice and rat studies

Keywords

biological techniques; data acquisition; image resolution; photomultipliers; positron emission tomography; single photon emission computed tomography; 0.15 mm to 4 cm; NIM-CAMAC standard electronics; Pb; YAP:Ce; YAlO3:Ce; integrated PET-SPECT small animal imager; lead collimators; mice studies; position sensitive photomultipliers; rat studies; read-out; rotating detectors; spatial resolution; Animals; Collimators; Crystals; Data acquisition; Fingers; Mice; Photomultipliers; Position sensitive particle detectors; Positron emission tomography; Spatial resolution;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/23.873012

Filename

873012