DocumentCode :
139817
Title :
Spectral analysis of resting state magnetoencephalogram activity in patients with bipolar disorder
Author :
Al-Timemy, Ali H. ; Fernandez, Alicia ; Escudero, Javier
Author_Institution :
Biomed. Eng. Dept., Baghdad Univ., Baghdad, Iraq
fYear :
2014
fDate :
26-30 Aug. 2014
Firstpage :
2197
Lastpage :
2200
Abstract :
We analyzed the frequency spectrum of magnetoencephalogram (MEG) background activity in 16 bipolar disorder (BD) patients and 24 age-matched healthy control. Median frequency (MF), spectral entropy (SpEn), and relative power in delta (RPδ), theta (RPθ), alpha (RPα), beta (RPβ), and gamma (RPγ) bands were computed for all 148 MEG channels. Significant differences between the two groups were found in the average level of MF, RPδ, and RPθ in the posterior region of the scalp. Moreover, the MF, SpEn, RPδ, and RPβ values of BD patients had a different dependence on age as compared with the results of control subjects, which may suggest that BD affects how the brain activity develops with age. We conclude that the spectral analysis of the background MEG in BD patients may give insights into how this condition affects the brain activity.
Keywords :
bioelectric potentials; entropy; magnetoencephalography; medical disorders; medical signal detection; medical signal processing; neurophysiology; spectral analysis; bipolar disorder patients; brain activity; median frequency spectrum analysis; resting state magnetoencephalogram activity; spectral entropy; Brain; Coherence; Diseases; Electroencephalography; Magnetic recording; Spectral analysis; Synchronization;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
ISSN :
1557-170X
Type :
conf
DOI :
10.1109/EMBC.2014.6944054
Filename :
6944054
Link To Document :
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