Title :
A novel device to preserve intestinal tissue Ex-Vivo by cold peristaltic perfusion
Author :
Narayan, Raja R. ; Pancer, Natalie E. ; Loeb, Brian W. ; Oki, Kristi ; Crouch, Andrew ; Backus, Spencer ; Chauhan, Yusuf ; Patron-Lozano, Roger ; Rodriguez-Davalos, Manuel I. ; Geibel, John P. ; Fan, Richard E. ; Zinter, Joseph P.
Author_Institution :
Sch. of Public Health, Yale Univ., New Haven, CT, USA
Abstract :
In the past two decades, much advancement has been made in the area of organ procurement and preservation for the transplant of kidneys, livers, and lungs. However, small intestine preservation remains unchanged. We propose a new preservation system for intestinal grafts that has the potential to increase the viability of the organ during transport. When experimented with porcine intestine, our device resulted in superior tissue quality than tissue in standard of care.
Keywords :
biological organs; biological tissues; biomedical engineering; haemorheology; cold peristaltic perfusion; intestinal grafts; intestinal tissue; kidneys; livers; lungs; organ preservation; organ procurement; organ viability; porcine intestine; small intestine preservation; tissue quality; Educational institutions; Ice; Intestines; Procurement; Pumps; Standards; Surgery;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
DOI :
10.1109/EMBC.2014.6944283