Title :
Osteoinductive Calcium Phosphate clay nanoparticle bone cements (CPCs) with enhanced mechanical properties
Author :
Jammalamadaka, Udayabhanu ; Tappa, Karthik ; Mills, D.
Abstract :
Calcium Phosphate Cements (CPCs) with osteoconductive properties are limited in their applications because of their poor mechanical properties. This study investigated the additive effect of Dexamethasone-doped Halloysite Nanotubes (HNTs on the mechanical properties of CPCs. HNTs are nanosized tubes with alumino-silicate composition. Physico-chemical properties, cytocompatability and cellular functionality of the nanocomposites were assayed. Results suggest that these nanoenhanced composites have a huge potential to broaden the applications of CPCs.
Keywords :
alumina; bioceramics; bone; calcium compounds; cellular biophysics; clay; mechanical properties; nanocomposites; nanomedicine; nanoparticles; nanotubes; silicon compounds; tissue engineering; Al2O3-SiO2; alumino-silicate composition; cellular functionality; cytocompatability; dexamethasone-doped halloysite nanotubes; mechanical property enhancement; nanocomposite enhancement; nanoparticle bone cements; osteoinductive calcium phosphate clay; physico-chemical properties; Bones; Calcium; Chemicals; Liquids; Mechanical factors; Nanotubes; Surface topography;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
DOI :
10.1109/EMBC.2014.6944480
