Automatic montaging of corneal sub-basal nerve images for the composition of a wide-range mosaic

We present and discuss a computerized system able to provide a wide-range mosaic of the sub-basal nerve layer of central cornea, built from several images acquired in-vivo with confocal microscopy. The montage is performed by a fast, reliable and fully automatic computerized system that does not require any expedient or manual adjustment during the acquisition process. The resulting mosaic provides a large high quality image, which should significantly aid clinicians in evaluating and assessing in a more reliable way the pathologic signs of interest.