DocumentCode
1413790
Title
Bionic pancreas
Author
Upson, Sandra
Volume
48
Issue
1
fYear
2011
Firstpage
11
Lastpage
11
Abstract
Biomedical engineers at Imperial College London designed an intelligent insulin pump for diabetes patients. This biomimetic approach diverges from today´s dominant method of delivering only insulin using a relatively simple control system. In a small clinical trial of 10 patients, they have been testing a device controlled by the microchip´s cell models at two London hospitals. The device will infuse both insulin and glucagon by following a pattern that mimics the unique electrical characteristics of alpha and beta cells.The device consists of an electrochemical glucose sensor that penetrates the skin, the microchip, and two small pumps worn on the body, one for each hormone. Every 5 minutes, the sensor detects the person´s glucose level. If the sensor reports a high level of glucose, the silicon beta cell generates a signal that drives a motor. The motor pushes a syringe, dispensing insulin into the tissue beneath the skin until the glucose reading at the sensor drops and the beta cell goes silent.
Keywords
bioelectric phenomena; biomedical electronics; biomedical equipment; biomimetics; biosensors; electrochemical sensors; medical control systems; micropumps; organic compounds; sugar; Imperial College London; alpha cells; beta cells; biomimetic approach; bionic pancreas; diabetes patients; electrical characteristics; electrochemical glucose sensor; glucagon; intelligent insulin pump; microchip cell models; motor; skin tissue; syringe; Biomedical engineering; Diabetes; Insulin; Pancreas; Pumps;
fLanguage
English
Journal_Title
Spectrum, IEEE
Publisher
ieee
ISSN
0018-9235
Type
jour
DOI
10.1109/MSPEC.2011.5676365
Filename
5676365
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