• DocumentCode
    1413790
  • Title

    Bionic pancreas

  • Author

    Upson, Sandra

  • Volume
    48
  • Issue
    1
  • fYear
    2011
  • Firstpage
    11
  • Lastpage
    11
  • Abstract
    Biomedical engineers at Imperial College London designed an intelligent insulin pump for diabetes patients. This biomimetic approach diverges from today´s dominant method of delivering only insulin using a relatively simple control system. In a small clinical trial of 10 patients, they have been testing a device controlled by the microchip´s cell models at two London hospitals. The device will infuse both insulin and glucagon by following a pattern that mimics the unique electrical characteristics of alpha and beta cells.The device consists of an electrochemical glucose sensor that penetrates the skin, the microchip, and two small pumps worn on the body, one for each hormone. Every 5 minutes, the sensor detects the person´s glucose level. If the sensor reports a high level of glucose, the silicon beta cell generates a signal that drives a motor. The motor pushes a syringe, dispensing insulin into the tissue beneath the skin until the glucose reading at the sensor drops and the beta cell goes silent.
  • Keywords
    bioelectric phenomena; biomedical electronics; biomedical equipment; biomimetics; biosensors; electrochemical sensors; medical control systems; micropumps; organic compounds; sugar; Imperial College London; alpha cells; beta cells; biomimetic approach; bionic pancreas; diabetes patients; electrical characteristics; electrochemical glucose sensor; glucagon; intelligent insulin pump; microchip cell models; motor; skin tissue; syringe; Biomedical engineering; Diabetes; Insulin; Pancreas; Pumps;
  • fLanguage
    English
  • Journal_Title
    Spectrum, IEEE
  • Publisher
    ieee
  • ISSN
    0018-9235
  • Type

    jour

  • DOI
    10.1109/MSPEC.2011.5676365
  • Filename
    5676365