Title :
Efficient Optical Pattern Detection for Microcavity Sensors Based Lab-on-a-Chip
Author :
Cao, Yingjie ; Zhu, Yongxin ; Rong, Guoguang ; Lin, Zhongduo ; Wang, Guoxing ; Gu, Zonghua ; Sawan, Mohamad
Author_Institution :
Sch. of Microelectron., Shanghai Jiao Tong Univ., Shanghai, China
fDate :
6/1/2012 12:00:00 AM
Abstract :
A framework of optical lab-on-a-chip using porous silicon microcavity membrane is presented in this paper. With measured results of the membrane, reflectance spectra detection is designed and implemented on FPGA. We manage to detect the shift of the resonant dip to distinguish target molecule solution of different concentration. To evaluate the feasibility of lab-on-a-chip, we further model the cost and performance of on-chip optical sensors and data processing system. The novel optical lab-on-a-chip will enable detection of biological samples at a much higher sensitivity than classic electrochemical methods. The efficient detecting algorithm will ensure the speed of pattern detection even when the lab-on-a-chip system has to deal with data from multiple channels.
Keywords :
biosensors; computerised instrumentation; electrochemical sensors; field programmable gate arrays; lab-on-a-chip; microsensors; optical sensors; FPGA; biological sample detection algorithm; data processing system; electrochemical method; microcavity sensor; multiple channels; optical lab-on-a-chip sensor; optical pattern detection; porous silicon microcavity membrane; reflectance spectra detection; resonant dip shift detection; target molecule solution; Detectors; Hardware; Maximum likelihood detection; Nonlinear filters; Optical reflection; Optical sensors; Lab-on-a-chip; microcavity; optical biosensor; porous silicon;
Journal_Title :
Sensors Journal, IEEE
DOI :
10.1109/JSEN.2011.2182645