Title :
Modeling Cellular Lysis in Skeletal Muscle Due to Electric Shock
Author :
Cela, Carlos J. ; Lee, Raphael C. ; Lazzi, Gianluca
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Utah, Salt Lake City, UT, USA
fDate :
5/1/2011 12:00:00 AM
Abstract :
High-voltage electrical trauma frequently results in injury patterns that cannot be completely attributed to Joule heating. An electrical-injury model describing cellular lysis damage caused by supraphysiological electric fields is introduced, and used to evaluate the effects of high-voltage electric shock on the skeletal muscle of a human upper limb in a configuration that simulates hand-to-hand contact. A novel multiresolution admittance method, capable of efficiently handling large computational models while maintaining excellent accuracy, was used to perform the numerical computations. Values for the computed current through the arm and the upper limb impedance are reported.
Keywords :
biochemistry; biological effects of fields; biomedical measurement; cellular effects of radiation; electric admittance measurement; electric shocks; electrolysis; injuries; muscle; Joule heating; cellular lysis; electric shock effect; electrical-injury model; hand-to-hand contact; high-voltage electrical trauma; human upper limb; injury patterns; multiresolution admittance method; numerical computation; skeletal muscle; supraphysiological electric fields; Admittance; Conductivity; Electric shock; Injuries; Mathematical model; Muscles; Numerical models; Bioimpedance; electric shock; finite difference methods; injuries; multigrid methods; numerical simulation; Algorithms; Arm; Cell Death; Computer Simulation; Electric Injuries; Humans; Models, Biological; Muscle, Skeletal;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2010.2103362