Title :
A Linear Representation of Dynamics of Boolean Networks
Author :
Cheng, Daizhan ; Qi, Hongsheng
Author_Institution :
Key Lab. of Syst. & Control, Chinese Acad. of Sci., Beijing, China
Abstract :
A new matrix product, called semi-tensor product of matrices, is reviewed. Using it, a matrix expression of logic is proposed, where a logical variable is expressed as a vector, a logical function is expressed as a multiple linear mapping. Under this framework, a Boolean network equation is converted into an equivalent algebraic form as a conventional discrete-time linear system. Analyzing the transition matrix of the linear system, formulas are obtained to show a) the number of fixed points; b) the numbers of cycles of different lengths; c) transient period, for all points to enter the set of attractors; and d) basin of each attractor. The corresponding algorithms are developed and used to some examples.
Keywords :
Boolean functions; biocomputing; cellular biophysics; discrete time systems; linear systems; matrix algebra; tensors; Boolean network equation; discrete-time linear system; linear mapping; linear representation; logical function; matrix expression; matrix product; semi-tensor product of matrices; transition matrix; Biological system modeling; Cells (biology); Equations; Land mobile radio cellular systems; Linear systems; Logic; Matrix converters; Proteins; State-space methods; Systems biology; Boolean network; cycle; fixed point; semi-tensor product; transient period;
Journal_Title :
Automatic Control, IEEE Transactions on
DOI :
10.1109/TAC.2010.2043294