Initial Evaluation of LabPET/SPECT Dual Modality Animal Imaging System

Author

Rutao Yao ; Xiao Deng ; Beaudoin, Jean-Francois ; Tianyu Ma ; Cadorette, Jules ; Zixiong Cao ; Lecomte, Roger

Author_Institution

Dept. of Nucl. Med., State Univ. of New York (SUNY) at Buffalo, Buffalo, NY, USA

Volume

60

Issue

1

fYear

2013

fDate

Feb. 2013

Firstpage

76

Lastpage

81

Abstract

We developed SPECT imaging capability on a LabPET animal scanner to provide an integrated PET/SPECT dual-modality imaging system. The add-on SPECT sub-system was enabled by 1) mechanically integrating a multiple-pinhole collimator in the PET detector ring, and 2) configuring the detectors to acquire singles events in the 120-160 keV range. We report on the design parameters, data acquisition protocols and initial performance assessment of this cost-effective SPECT imaging solution. Phantom and animal images demonstrating the relevance of the system for various imaging tasks in preclinical research are presented.

Keywords

collimators; positron emission tomography; single photon emission computed tomography; LabPET animal scanner; LabPET/SPECT; PET detector ring; SPECT imaging capability; cost effective SPECT imaging; dual modality animal imaging system; electron volt energy 120 keV to 160 keV; multiple pinhole collimator; Collimators; Detectors; Mice; Positron emission tomography; Single photon emission computed tomography; Animal dual-modality imaging; PET/SPECT; multiple pinhole collimator;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/TNS.2012.2233216

Filename

6413261