DocumentCode
1426821
Title
The Minimum Entropy Mapping Spectrum of a DNA Sequence
Author
Galleani, Lorenzo ; Garello, Roberto
Author_Institution
Dept. of Electr. Eng., Politec. di Torino, Torino, Italy
Volume
56
Issue
2
fYear
2010
Firstpage
771
Lastpage
783
Abstract
Periodicities in a DNA sequence contain information about its function and structure. Frequency analysis can be used to reveal such periodicities. A definition of spectrum for DNA sequences is proposed, based on an entropy minimization criterion. It is shown that the properties of the proposed spectrum are those expected from the spectrum of a symbolic sequence. Applications to simulated and experimental DNA sequences are presented and compared against classical techniques to prove the effectiveness of the proposed method.
Keywords
DNA; biological techniques; genomics; minimum entropy methods; molecular biophysics; numerical analysis; DNA function; DNA sequence periodicities; DNA structure; entropy minimization criterion; frequency analysis; minimum entropy mapping spectrum; symbolic sequence; Bioinformatics; DNA; Discrete Fourier transforms; Entropy; Frequency; Genomics; Sequences; Signal analysis; Signal mapping; Signal processing; DNA periodicities; genomic signal processing; spectral analysis; symbolic sequence; time-frequency analysis;
fLanguage
English
Journal_Title
Information Theory, IEEE Transactions on
Publisher
ieee
ISSN
0018-9448
Type
jour
DOI
10.1109/TIT.2009.2037041
Filename
5420281
Link To Document