Title :
The subcutaneous route to insulin dependent diabetes therapy
Author :
Bellazzi, Riccardo ; Nucci, Gianluca ; Cobelli, Claudio
Author_Institution :
Dipt. di Inf. e Sistemistica, Pavia Univ., Italy
Abstract :
Discusses closed-loop and partially closed-loop control strategies for insulin delivery and measuring glucose concentration. The authors review the subcutaneous closed- and partially closed-loop strategies that have been proposed and tested in recent years for insulin-dependent diabetes therapy. Focus is on control, modeling, and information technology aspects, and future directions of research are also outlined. This survey complements earlier reviews concerning control approaches and application of computers in diabetes care
Keywords :
biocontrol; diseases; organic compounds; patient treatment; physiological models; reviews; skin; diabetes care; future research directions; glucose concentration measurement; information technology; insulin dependent diabetes therapy; modeling; partially closed-loop control strategies; subcutaneous route; Blood; Diabetes; Feedback control; Feedforward systems; Insulin; Least squares approximation; Medical treatment; Plasmas; Safety; Sugar;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
