Demonstration of in-vivo Multi-Probe Tracker Based on a Si/CdTe Semiconductor Compton Camera

Author

Takeda, Shin Ichiro ; Odaka, Hirokazu ; Ishikawa, Shin-nosuke ; Watanabe, Shin ; Aono, Hiroyuki ; Takahashi, Tadayuki ; Kanayama, Yousuke ; Hiromura, Makoto ; Enomoto, Shuichi

Volume

59

Issue

1

fYear

2012

Firstpage

70

Lastpage

76

Abstract

By using a prototype Compton camera consisting of silicon (Si) and cadmium telluride (CdTe) semiconductor detectors, originally developed for the ASTRO-H satellite mission, an experiment involving imaging multiple radiopharmaceuticals injected into a living mouse was conducted to study its feasibility for medical imaging. The accumulation of both iodinated (¹³¹I) methylnorcholestenol and ⁸⁵Sr into the mouse´s organs was simultaneously imaged by the prototype. This result implies that the Compton camera is expected to become a multi-probe tracker available in nuclear medicine and small animal imaging.

Keywords

Compton effect; II-VI semiconductors; biomedical equipment; biomedical imaging; cadmium compounds; elemental semiconductors; radioisotope imaging; semiconductor counters; silicon; ASTRO-H satellite mission; Si-CdTe; cadmium telluride semiconductor detectors; imaging multiple radiopharmaceuticals; in-vivo multiprobe tracker based demonstration; iodinated methylnorcholestenol; living mouse; medical imaging; mouses organs; multiprobe tracker; nuclear medicine; satellite mission; semiconductor Compton camera; silicon semiconductor detectors; small animal imaging; Cameras; Decision support systems; Detectors; Mice; Scattering; Silicon; Astrophysics; Si/CdTe semiconductor compton camera; nuclear medicine; small animal imaging;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/TNS.2011.2178432

Filename

6140939