Malignant tumor and atherosclerotic plaque diagnosis using laser-induced fluorescence

Author

Andersson-Engels, Stefan ; Johansson, Jonas ; Stenram, Unne ; Svanberg, K. ; Svanberg, S.

Author_Institution

Dept. of Phys., Lund Inst. of Technol., Sweden

Volume

26

Issue

12

fYear

1990

fDate

12/1/1990 12:00:00 AM

Firstpage

2207

Lastpage

2217

Abstract

A review of tissue diagnostics using laser-induced fluorescence is given with illustrations chosen from work performed by the authors´ group. Two major topics are considered: the demarcation of malignant tumors from normal surrounding tissue and the identification of atherosclerotic regions in arteries. Specific fluorescence from injected agents and tissue natural autofluorescence are discussed. Steady-state and time-resolved fluorescence can be utilized. Original data showing immunity to blood interference in artery monitoring are presented. Imaging techniques for diseased tissue real-time visualization are discussed and illustrated

Keywords

biomedical measurement; fluorescence; laser applications in medicine; patient diagnosis; reviews; arteries; artery monitoring; atherosclerotic plaque diagnosis; blood interference; diseased tissue real-time visualization; imaging techniques; injected agents; laser-induced fluorescence; malignant tumor; review; time-resolved fluorescence; tissue diagnostics; tissue natural autofluorescence; Biomedical imaging; Cancer; Fluorescence; Malignant tumors; Medical diagnostic imaging; Monitoring; Optical pulses; Physics; Spectroscopy; Steady-state;

fLanguage

English

Journal_Title

Quantum Electronics, IEEE Journal of

Publisher

ieee

ISSN

0018-9197

Type

jour

DOI

10.1109/3.64357

Filename

64357