Title :
Simulating the Electro-Mechanical Behavior of Skeletal Muscles
Author_Institution :
Univ. of Stuttgart, Stuttgart, Germany
Abstract :
Computational models of the human body must be accurate enough to use in hypothesis testing or biological function analysis. This is possible only when such models use physiological information from different scales-such as the cell, tissue, and organ levels. This model of excitation-contraction coupling in skeletal muscles links cell-level electro-physiological behavior with organ-level biomechanical behavior.
Keywords :
biology computing; muscle; biological function analysis; cell level electro-physiological behavior; computational models; electromechanical behavior; excitation contraction; human body; hypothesis testing; physiological information; skeletal muscles; Biological system modeling; Biology computing; Computational modeling; Elasticity; Heart; Humans; Joining processes; Muscles; Musculoskeletal system; Testing; Skeletal muscle modeling; biodomain equations; cellular modeling; coupling; excitation-contraction; finite elasticity; multiscale modeling; scientific computing;
Journal_Title :
Computing in Science & Engineering
DOI :
10.1109/MCSE.2010.30