Title :
Mapping the human retina
Author :
Pinz, Axel ; Bernögger, Stefan ; Datlinger, Peter ; Kruger, Andreas
Author_Institution :
Inst. for Comput. Graphics & Vision, Graz Univ. of Technol., Austria
Abstract :
The new therapeutic method of scotoma-based photocoagulation (SBP) developed at the Vienna Eye Clinic for diagnosis and treatment of age-related macular degeneration requires retinal maps from scanning laser ophthalmoscope images. This paper describes in detail all necessary image analysis steps for map generation. A prototype software system for fully automatic map generation has been implemented and tested on a representative dataset selected from a clinical study with 50 patients. The map required for the SBP treatment can be reliably extracted in all cases. Thus, algorithms presented in this paper should be directly applicable in daily clinical routine without major modifications.
Keywords :
eye; feature extraction; image registration; laser applications in medicine; medical image processing; Vienna Eye Clinic; age-related macular degeneration; algorithms; clinical study; human retina mapping; image analysis steps; medical diagnostic imaging; prototype software system; representative dataset; scanning laser ophthalmoscope images; scotoma-based photocoagulation; therapeutic method; Automatic testing; Feature extraction; Humans; Image analysis; Retina; Software prototyping; Software systems; Software testing; Spatial resolution; System testing; Algorithms; Humans; Lasers; Light Coagulation; Macular Degeneration; Ophthalmoscopy; Retina;
Journal_Title :
Medical Imaging, IEEE Transactions on