DocumentCode
1449553
Title
Partial Least Squares: A Method to Estimate Efficient Channels for the Ideal Observers
Author
Witten, Joel M. ; Park, Subok ; Myers, Kyle J.
Author_Institution
Div. of Imaging & Appl. Math., Food & Drug Adm. (FDA), White Oak, MD, USA
Volume
29
Issue
4
fYear
2010
fDate
4/1/2010 12:00:00 AM
Firstpage
1050
Lastpage
1058
Abstract
We advocate a task-based approach to the assessment of image quality using the Bayesian ideal observer. The Bayesian ideal observer provides an absolute upper bound for performance estimates. However, using the full images as inputs to the observer is often infeasible due to their high dimensionality. A practical alternative is to reduce the dimensionality of the images by applying channels, while approximating the ideal observer by an observer constrained to the channels. Laguerre-Gauss (LG) channels and those derived from the singular value decomposition (SVD) of the system operator have previously been used with the Bayesian ideal observer. However, the channelized observer with LG and SVD channels was only applicable in situations with a rotationally symmetric signal or known system operator, respectively. We investigate a method using partial least squares (PLS) to compute efficient channels directly from the images, without prior knowledge of the background, signal, or system operator. Results show that the channelized ideal observer with PLS channels approximates the nonchannelized observer, and does so with fewer channels than the observer with either LG or SVD channels. The images are reduced from 4096 pixel values to 20 channel outputs, yet preserve the salient information. Furthermore, PLS reveals that the background image statistics provide important information necessary in signal-detection tasks. Overall, PLS is shown to be a viable channel generation method and may be applicable to real-life situations.
Keywords
Bayes methods; least squares approximations; medical image processing; Bayesian ideal observer; LG channel comparison; SVD channel comparison; background image statistics; channel generation method; efficient channel estimation; image dimensionality reduction; image quality assessment; nonchannelised observer; partial least squares; performance estimate upper bound; signal detection tasks; task based approach; Bayesian methods; Drugs; Humans; Image quality; Least squares approximation; Least squares methods; Mathematics; Neoplasms; Statistics; Upper bound; Bayesian ideal observer; channelized Hotelling observer; channelized ideal observer; efficient channels; image quality; partial least squares; Algorithms; Artificial Intelligence; Bayes Theorem; Computer Simulation; Image Enhancement; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Least-Squares Analysis; Models, Biological; Models, Statistical; Observer Variation; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity;
fLanguage
English
Journal_Title
Medical Imaging, IEEE Transactions on
Publisher
ieee
ISSN
0278-0062
Type
jour
DOI
10.1109/TMI.2010.2041514
Filename
5437341
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