DocumentCode
1449591
Title
Response to Letter Regarding Article: “Developing DCE-CT to Quantify Intra-Tumor Heterogeneity in Breast Tumors With Differing Angiogenic Phenotype”
Author
Cao, Minsong ; Liang, Yun ; Stantz, Keith M.
Author_Institution
Sch. of Health Sci., Purdue Univ., West Lafayette, IN, USA
Volume
29
Issue
4
fYear
2010
fDate
4/1/2010 12:00:00 AM
Firstpage
1089
Lastpage
1092
Abstract
In this response letter, technical issues raised by the comments concerning determination of arterial input function, cardiac and respiratory related motion artifacts, contrast agent application, and compartmental model fitting in our work are addressed in detail, and a discussion on identifying causes of uncertainty in physiological measurement and how to minimize their contribution is presented.
Keywords
computerised tomography; mammography; physiology; tumours; DCE-CT development; angiogenic phenotype; arterial input function; breast tumors; cardiac related motion artifacts; compartmental model fitting; contrast agent application; dynamic contrast enhanced computed tomography; intratumor heterogeneity; physiological measurement; respiratory related motion artifacts; Compartmental model; dynamic contrast enhanced computed tomography (DCE-CT); tumor heterogeneity;
fLanguage
English
Journal_Title
Medical Imaging, IEEE Transactions on
Publisher
ieee
ISSN
0278-0062
Type
jour
DOI
10.1109/TMI.2009.2039224
Filename
5437346
Link To Document