Title :
The effect of alternating current at intermediate frequency on MCF-7 and cell cycle in vitro
Author :
Ma Jun ; Tang Jintian
Author_Institution :
Dept. of Biopharmaceuticals, Beijing Univ. of Chinese Med., Beijing, China
Abstract :
The aim of the present study is to investigate the inhibition of alternating current at intermediate frequency (ACIF) on human breast cancer cells MCF-7 in vitro. Influencing effect was different parameters dependent (frequency, electric current, duration). Then the possible mechanism of ACIF inhibition on tumor cell proliferation in vitro was that ACIF could induce suppression of DNA synthesis in S phase, cell mitosis and cell apoptosis.
Keywords :
biomedical engineering; cancer; cellular biophysics; patient treatment; ACIF inhibition; DNA synthesis; MCF-7; S phase; alternating current inhibition; cell apoptosis; cell cycle; cell mitosis; human breast cancer cells; intermediate frequency; tumor cell proliferation; Breast cancer; Current; Educational institutions; Electric fields; In vitro; Tumors; Alternating current at intermediate frequency (ACIF); Apoptosis; Cell cycle; human breast cancer cells (MCF-7);
Conference_Titel :
Information Science, Electronics and Electrical Engineering (ISEEE), 2014 International Conference on
Conference_Location :
Sapporo
Print_ISBN :
978-1-4799-3196-5
DOI :
10.1109/InfoSEEE.2014.6948200
