DocumentCode
1463079
Title
Extrapolatable Analytical Functions for Tendon Excursions and Moment Arms From Sparse Datasets
Author
Kurse, Manish U. ; Lipson, Hod ; Valero-Cuevas, Francisco J.
Author_Institution
Dept. of Biomed. Eng., Univ. of Southern California, Los Angeles, CA, USA
Volume
59
Issue
6
fYear
2012
fDate
6/1/2012 12:00:00 AM
Firstpage
1572
Lastpage
1582
Abstract
Computationally efficient modeling of complex neuromuscular systems for dynamics and control simulations often requires accurate analytical expressions for moment arms over the entire range of motion. Conventionally, polynomial expressions are regressed from experimental data. But these polynomial regressions can fail to extrapolate, may require large datasets to train, are not robust to noise, and often have numerous free parameters. We present a novel method that simultaneously estimates both the form and parameter values of arbitrary analytical expressions for tendon excursions and moment arms over the entire range of motion from sparse datasets. This symbolic regression method based on genetic programming has been shown to find the appropriate form of mathematical expressions that capture the physics of mechanical systems. We demonstrate this method by applying it to 1) experimental data from a physical tendon-driven robotic system with arbitrarily routed multiarticular tendons and 2) synthetic data from musculoskeletal models. We show it outperforms polynomial regressions in the amount of training data, ability to extrapolate, robustness to noise, and representation containing fewer parameters-all critical to realistic and efficient computational modeling of complex musculoskeletal systems.
Keywords
bone; extrapolation; genetic algorithms; medical robotics; muscle; neuromuscular stimulation; regression analysis; complex neuromuscular system; control simulation; dynamics simulation; extrapolatable analytical function; genetic programming; moment arms; multiarticular tendon; musculoskeletal model; physical tendon-driven robotic system; sparse datasets; symbolic regression method; tendon excursion; Extrapolation; Joints; Mathematical model; Polynomials; Robots; Tendons; Training; Extrapolation; moment arm; polynomial regression; symbolic regression; tendon excursions; Algorithms; Animals; Computer Simulation; Databases, Factual; Humans; Joints; Models, Biological; Tendons; Torque;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.2012.2189771
Filename
6164249
Link To Document