Title :
Determining the temperature distribution of a model vessel wall under pulsed laser irradiation: an experimental attempt to measure fibrous cap thickness and detect temperature elevation in atherosclerotic lesions
Author :
Matsui, Takemi ; Arai, Tsunenori ; Sato, Shunichi ; Suzuki, Minoru ; Ishizuka, Toshiaki ; Kikuchi, Makoto ; Kurita, Akira
Author_Institution :
Med. Coll., national Defense Med. Coll., Tokorozawa, Japan
fDate :
4/1/2001 12:00:00 AM
Abstract :
In order to measure the temperature of atherosclerotic plaques, the authors developed a method to determine the temperature distribution of vessel walls using a three-layer phantom agar model. Under pulsed-laser irradiation, the thickness of upper layer corresponding to fibrous cap overlying the middle layer corresponding to atherosclerotic lesion could be calculated. The temperature was calculated from measured temperature changes under pulsed-laser irradiation.
Keywords :
blood vessels; diseases; laser applications in medicine; temperature distribution; temperature measurement; atherosclerotic lesion; atherosclerotic plaques temperature measurement; fibrous cap thickness measurement; inflammation; model vessel wall temperature distribution determination; pulsed laser irradiation; three-layer phantom agar model; upper layer thickness; Arteries; Biomedical measurements; Humans; Imaging phantoms; Laser modes; Lesions; Optical pulses; Pulse measurements; Temperature distribution; Temperature measurement; Aorta; Arteries; Arteriosclerosis; Endothelium, Vascular; Heat; Humans; Lasers; Models, Cardiovascular; Phantoms, Imaging; Rupture, Spontaneous;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
