Determining the temperature distribution of a model vessel wall under pulsed laser irradiation: an experimental attempt to measure fibrous cap thickness and detect temperature elevation in atherosclerotic lesions

Author

Matsui, Takemi ; Arai, Tsunenori ; Sato, Shunichi ; Suzuki, Minoru ; Ishizuka, Toshiaki ; Kikuchi, Makoto ; Kurita, Akira

Author_Institution

Med. Coll., national Defense Med. Coll., Tokorozawa, Japan

Volume

48

Issue

4

fYear

2001

fDate

4/1/2001 12:00:00 AM

Firstpage

492

Lastpage

495

Abstract

In order to measure the temperature of atherosclerotic plaques, the authors developed a method to determine the temperature distribution of vessel walls using a three-layer phantom agar model. Under pulsed-laser irradiation, the thickness of upper layer corresponding to fibrous cap overlying the middle layer corresponding to atherosclerotic lesion could be calculated. The temperature was calculated from measured temperature changes under pulsed-laser irradiation.

Keywords

blood vessels; diseases; laser applications in medicine; temperature distribution; temperature measurement; atherosclerotic lesion; atherosclerotic plaques temperature measurement; fibrous cap thickness measurement; inflammation; model vessel wall temperature distribution determination; pulsed laser irradiation; three-layer phantom agar model; upper layer thickness; Arteries; Biomedical measurements; Humans; Imaging phantoms; Laser modes; Lesions; Optical pulses; Pulse measurements; Temperature distribution; Temperature measurement; Aorta; Arteries; Arteriosclerosis; Endothelium, Vascular; Heat; Humans; Lasers; Models, Cardiovascular; Phantoms, Imaging; Rupture, Spontaneous;

fLanguage

English

Journal_Title

Biomedical Engineering, IEEE Transactions on

Publisher

ieee

ISSN

0018-9294

Type

jour

DOI

10.1109/10.915717

Filename

915717