Flow Control of Small Objects on Chip: Manipulating Live Cells, Quantum Dots, and Nanowires

Author

Probst, Roland ; Cummins, Zachary ; Ropp, Chad ; Waks, Edo ; Shapiro, Benjamin

Author_Institution

Fischell Dept. of Bioeng., Univ. of Maryland, College Park, MD, USA

Volume

32

Issue

2

fYear

2012

fDate

4/1/2012 12:00:00 AM

Firstpage

26

Lastpage

53

Abstract

This article is on microscale flow control, on dynamically shaping flow fields in microfluidic devices to precisely manipulate cells, quantum dots (QDs), and nanowires. Compared to prior methods, manipulating microscopic and nanoscopic objects by flow control can be achieved with simpler and easy-to-fabricate devices, can steer a wider variety of objects, and enables entirely new capabilities such as placement and immobilization of specific quantum dots to desired on-chip locations with nanoscale precision. A companion article investigates flow control in the body and develops methods to shape magnetic fields to direct ferrofluids of therapeutic magnetic nanoparticles to disease locations in patients.

Keywords

flow control; medical control systems; microfluidics; nanowires; quantum dots; dynamically shaping flow fields; magnetic fields; manipulating live cells; manipulating microscopic object; manipulating nanoscopic object; microfluidic devices; microscale flow control; nanoscale precision; nanowires; on-chip locations; patient disease locations; quantum dots; therapeutic magnetic nanoparticles ferrofluids; Charge carrier processes; Laser beams; Magnetic resonance imaging; Microfluidics; Nanobioscience; Nanoscale devices;

fLanguage

English

Journal_Title

Control Systems, IEEE

Publisher

ieee

ISSN

1066-033X

Type

jour

DOI

10.1109/MCS.2011.2181584

Filename

6170790