Title :
Design Automation for Synthetic Biological Systems
Author :
Densmore, Douglas ; Hassoun, Soha
Author_Institution :
Boston Univ., Boston, MA, USA
fDate :
6/1/2012 12:00:00 AM
Abstract :
Through principled engineering methods, synthetic biology aims to build specialized biological components that can be modularly composed to create complex systems. This article outlines bio-design automation using two complementary design approaches, bottom-up modular construction from biological primitives and pathway-based approaches. The article also highlights future challenges for both.
Keywords :
CAD; biology computing; biodesign automation; biological primitives; bottom-up modular construction; complex system; engineering method; pathway-based approach; specialized biological component; synthetic biological system; Biological information theory; Biological systems; DNA; Molecular biophysics; Proteins; Electronic design automation; Genetic regulatory network; Metabolic engineering; Parts devices; Pathways; Synthetic biology; Systems; Systems biology;
Journal_Title :
Design & Test of Computers, IEEE
DOI :
10.1109/MDT.2012.2193370
