DocumentCode
1485091
Title
Design Automation for Synthetic Biological Systems
Author
Densmore, Douglas ; Hassoun, Soha
Author_Institution
Boston Univ., Boston, MA, USA
Volume
29
Issue
3
fYear
2012
fDate
6/1/2012 12:00:00 AM
Firstpage
7
Lastpage
20
Abstract
Through principled engineering methods, synthetic biology aims to build specialized biological components that can be modularly composed to create complex systems. This article outlines bio-design automation using two complementary design approaches, bottom-up modular construction from biological primitives and pathway-based approaches. The article also highlights future challenges for both.
Keywords
CAD; biology computing; biodesign automation; biological primitives; bottom-up modular construction; complex system; engineering method; pathway-based approach; specialized biological component; synthetic biological system; Biological information theory; Biological systems; DNA; Molecular biophysics; Proteins; Electronic design automation; Genetic regulatory network; Metabolic engineering; Parts devices; Pathways; Synthetic biology; Systems; Systems biology;
fLanguage
English
Journal_Title
Design & Test of Computers, IEEE
Publisher
ieee
ISSN
0740-7475
Type
jour
DOI
10.1109/MDT.2012.2193370
Filename
6178303
Link To Document