DocumentCode
1487493
Title
Direct Identification of Bacteria in Blood Culture Samples Using an Electronic Nose
Author
Trincavelli, Marco ; Coradeschi, Silvia ; Loutfi, Amy ; Söderquist, Bo ; Thunberg, Per
Author_Institution
Center for Appl. Autonomous Sensor Syst., Orebro Univ., Orebro, Sweden
Volume
57
Issue
12
fYear
2010
Firstpage
2884
Lastpage
2890
Abstract
In this paper, we introduce a method for identification of bacteria in human blood culture samples using an electronic nose. The method uses features, which capture the static (steady state) and dynamic (transient) properties of the signal from the gas sensor array and proposes a means to ensemble results from consecutive samples. The underlying mechanism for ensembling is based on an estimation of posterior probability, which is extracted from a support vector machine classifier. A large dataset representing ten different bacteria cultures has been used to validate the presented methods. The results detail the performance of the proposed algorithm and show that through ensembling decisions on consecutive samples, significant reliability in classification accuracy can be achieved.
Keywords
blood; cellular biophysics; electronic noses; medical computing; microorganisms; patient diagnosis; probability; support vector machines; bacteria cultures; bacteria direct identification; electronic nose; gas sensor array; human blood culture samples; patient diagnosis; posterior probability; support vector machine classifier; Antibiotics; Blood; Computerized monitoring; Data mining; Electronic noses; Gas detectors; Microorganisms; Sensor arrays; Support vector machine classification; Support vector machines; Bacteria identification; electronic nose; sepsis; Algorithms; Artificial Intelligence; Bacteremia; Bacteria; Bacteriological Techniques; Biosensing Techniques; Blood; Gases; Humans; Odors; Pattern Recognition, Automated; Reproducibility of Results; Signal Processing, Computer-Assisted;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.2010.2049492
Filename
5462872
Link To Document