Title :
Comment on "Developing DCE-CT to Quantify Intra-Tumor Heterogeneity in Breast Tumors With Differing Angiogenic Phenotype
Author :
Abramyuk, Andrij ; Wolf, Gunter ; Hietschold, Volker ; Haberland, Ulrike ; Van den Hoff, Joerg ; Abolmaali, Nasreddin
Author_Institution :
OncoRay, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany
fDate :
4/1/2010 12:00:00 AM
Abstract :
In our comment some essential issues concerning determination of arterial input function (AIF), cardiac and respiratory related motion artifacts, contrast agent application and compartmental model fitting done by Cao et al., 2009 are discussed.
Keywords :
Animals; Biomedical imaging; Breast tumors; Computed tomography; Heart; Medical diagnostic imaging; Mice; Muscles; Neoplasms; Plasma applications; Analysis of Variance; Animals; Breast Neoplasms; Contrast Media; Disease Models, Animal; Female; Histocytochemistry; Humans; Image Processing, Computer-Assisted; Iopamidol; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Phenotype; Positron-Emission Tomography; Reproducibility of Results; Statistics, Nonparametric; Tomography, X-Ray Computed; Transplantation, Heterologous;
Journal_Title :
Medical Imaging, IEEE Transactions on
DOI :
10.1109/TMI.2009.2031780