DocumentCode
1507857
Title
Design and Analysis of Molecular Relay Channels: An Information Theoretic Approach
Author
Nakano, Tadashi ; Liu, Jian-Qin
Author_Institution
Frontier Res. Center, Osaka Univ., Suita, Japan
Volume
9
Issue
3
fYear
2010
Firstpage
213
Lastpage
221
Abstract
In this paper, we consider a molecular relay channel in which signal molecules are transmitted by a sender of communication, propagated, amplified, removed in the channel, and sensed by the receiver of communication that decodes the signal molecules. To understand and characterize the communication capacity of the molecular relay channel, we develop an information communication model that consists of the transmitter, channel, and receiver. Mutual information is used to quantify the amount of information that is transferred from the transmitter through the channel to the receiver. The method employed and results presented in this paper may help elucidate design principles of biological systems as well as help in the design and engineering of synthetic biological systems from the perspective of information theory.
Keywords
biotransport; information theory; molecular biophysics; biological system design principles; communication capacity; information communication model; information theoretic approach; molecular relay channel analysis; molecular relay channel design; mutual information; signal molecule amplification; signal molecule decoding; signal molecule propagation; signal molecule transmission; synthetic biological systems; transmitter-channel-receiver model; Calcium signaling; molecular relay channel; mutual information; Algorithms; Calcium Signaling; Computer Simulation; Computers, Molecular; Information Theory; Models, Biological; Models, Molecular; Nanotechnology; Stochastic Processes;
fLanguage
English
Journal_Title
NanoBioscience, IEEE Transactions on
Publisher
ieee
ISSN
1536-1241
Type
jour
DOI
10.1109/TNB.2010.2050070
Filename
5477172
Link To Document