• DocumentCode
    1507857
  • Title

    Design and Analysis of Molecular Relay Channels: An Information Theoretic Approach

  • Author

    Nakano, Tadashi ; Liu, Jian-Qin

  • Author_Institution
    Frontier Res. Center, Osaka Univ., Suita, Japan
  • Volume
    9
  • Issue
    3
  • fYear
    2010
  • Firstpage
    213
  • Lastpage
    221
  • Abstract
    In this paper, we consider a molecular relay channel in which signal molecules are transmitted by a sender of communication, propagated, amplified, removed in the channel, and sensed by the receiver of communication that decodes the signal molecules. To understand and characterize the communication capacity of the molecular relay channel, we develop an information communication model that consists of the transmitter, channel, and receiver. Mutual information is used to quantify the amount of information that is transferred from the transmitter through the channel to the receiver. The method employed and results presented in this paper may help elucidate design principles of biological systems as well as help in the design and engineering of synthetic biological systems from the perspective of information theory.
  • Keywords
    biotransport; information theory; molecular biophysics; biological system design principles; communication capacity; information communication model; information theoretic approach; molecular relay channel analysis; molecular relay channel design; mutual information; signal molecule amplification; signal molecule decoding; signal molecule propagation; signal molecule transmission; synthetic biological systems; transmitter-channel-receiver model; Calcium signaling; molecular relay channel; mutual information; Algorithms; Calcium Signaling; Computer Simulation; Computers, Molecular; Information Theory; Models, Biological; Models, Molecular; Nanotechnology; Stochastic Processes;
  • fLanguage
    English
  • Journal_Title
    NanoBioscience, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    1536-1241
  • Type

    jour

  • DOI
    10.1109/TNB.2010.2050070
  • Filename
    5477172