Three-dimensional computation of light scattering from cells

Author

Dunn, Andrew ; Richards-Kortum, Rebecca

Author_Institution

Dept. of Electr. & Comput. Eng., Texas Univ., Austin, TX, USA

Volume

2

Issue

4

fYear

1996

fDate

12/1/1996 12:00:00 AM

Firstpage

898

Lastpage

905

Abstract

Using the finite-difference time-domain method, three-dimensional scattering patterns are computed for cells containing multiple organelles. The scattering cross section and average cosine of the scattering angle are computed for cells as a function of volume fraction of melanin granules and mitochondria. Results show that small organelles play a significant role in light scattering from cells, and the volume fraction of organelles affects both the total amount of scattered light and the angular distribution of scattered light

Keywords

Maxwell equations; biomedical imaging; cellular biophysics; finite difference time-domain analysis; laser applications in medicine; light scattering; angular distribution; cells; diagnostic optical imaging; finite-difference time-domain method; light scattering; melanin granules; mitochondria; multiple organelles; scattering angle average cosine; small organelles; three-dimensional computation; three-dimensional scattering patterns; volume fraction; Biomedical optical imaging; Cells (biology); Electromagnetic scattering; Finite difference methods; High-resolution imaging; Light scattering; Mie scattering; Optical refraction; Optical scattering; Time domain analysis;

fLanguage

English

Journal_Title

Selected Topics in Quantum Electronics, IEEE Journal of

Publisher

ieee

ISSN

1077-260X

Type

jour

DOI

10.1109/2944.577313

Filename

577313