DocumentCode
1525879
Title
Dual-molecule spectroscopy: molecular rulers for the study of biological macromolecules
Author
Ha, T. ; Enderle, Th. ; Chemla, D.S. ; Weiss, S.
Author_Institution
Div. of Mater. Sci., Lawrence Berkeley Lab., CA, USA
Volume
2
Issue
4
fYear
1996
fDate
12/1/1996 12:00:00 AM
Firstpage
1115
Lastpage
1128
Abstract
Single-molecule detection and spectroscopy by laser induced fluorescence offer many applications to life sciences. We review recent techniques and experiments based on the detection and spectroscopy of two near-by molecules. The spectroscopic signature of the light emitted from the two molecules can be used to measure the distance, orientation and relative dynamics between biological macromolecules
Keywords
biological techniques; fluorescence spectroscopy; intramolecular mechanics; molecular biophysics; molecular configurations; optical microscopy; reviews; biological macromolecules; distance; dual-molecule spectroscopy; fluorescence resonance energy transfer; molecular rulers; near field scanning optical microscope; orientation; relative dynamics; review; spectroscopic signature; two near-by molecules; Biomedical optical imaging; Chemical lasers; Fluorescence; Laser excitation; Laser theory; Molecular biophysics; Optical microscopy; Probes; Spectroscopy; Surface emitting lasers;
fLanguage
English
Journal_Title
Selected Topics in Quantum Electronics, IEEE Journal of
Publisher
ieee
ISSN
1077-260X
Type
jour
DOI
10.1109/2944.577342
Filename
577342
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