• DocumentCode
    1526693
  • Title

    Computerized detection of malignant tumors on digital mammograms

  • Author

    Kobatake, Hidefumi ; Murakami, Masayuki ; Takeo, Hideya ; Nawano, Sigeru

  • Author_Institution
    Grad. Sch. of Bio-Applications & Syst. Eng., Tokyo Univ. of Agric. & Technol., Japan
  • Volume
    18
  • Issue
    5
  • fYear
    1999
  • fDate
    5/1/1999 12:00:00 AM
  • Firstpage
    369
  • Lastpage
    378
  • Abstract
    This paper presents a tumor detection system for fully digital mammography. The processing scheme adopted in the proposed system focuses on the solution of two problems. One is how to detect tumors as suspicious regions with a very weak contrast to their background and another is how to extract features which characterize malignant tumors. For the first problem, a unique adaptive filter called the iris filter is proposed. It is very effective in enhancing approximately rounded opacities no matter what their contrasts might be. Clues for differentiation between malignant tumors and other tumors are believed to be mostly in their border areas. This paper proposes typical parameters which reflect boundary characteristics. To confirm the system performance for unknown samples, large scale experiments using 1212 CR images were performed. The results showed that the sensitivity of the proposed system was 90.5% and the average number of false positives per image was found to be only 1.3. These results show the effectiveness of the proposed system.
  • Keywords
    edge detection; feature extraction; image enhancement; mammography; medical image processing; tumours; adaptive filter; approximately rounded opacities; approximately rounded opacities enhancement; boundary detection; computer-aided diagnosis; computerized detection; contrast; digital mammograms; iris filter; large scale experiments; malignant tumors; medical diagnostic imaging; suspicious regions; Adaptive filters; Breast cancer; Computer aided diagnosis; Feature extraction; Iris; Large-scale systems; Malignant tumors; Mammography; Neoplasms; System performance; Algorithms; Breast Neoplasms; Diagnosis, Computer-Assisted; Diagnosis, Differential; Evaluation Studies as Topic; False Negative Reactions; False Positive Reactions; Female; Filtration; Humans; Mammography; Radiographic Image Enhancement; Sensitivity and Specificity;
  • fLanguage
    English
  • Journal_Title
    Medical Imaging, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0278-0062
  • Type

    jour

  • DOI
    10.1109/42.774164
  • Filename
    774164