An investigation of THz burn wound edema imaging using MRI

Author

Bajwa, Neha ; Nowroozi, Bryan ; Garritano, James ; Shijun Sung ; Tewari, Piyush ; Grundfest, Warren S. ; Taylor, Zeike

Author_Institution

Dept. of Bioeng., Univ. of California, Los Angeles, Los Angeles, CA, USA

fYear

2014

fDate

14-19 Sept. 2014

Firstpage

1

Lastpage

2

Abstract

Parallel T2 weighted multi slice multi echo (T2w MSME) 7T Magnetic Resonance (MR) scans and terahertz (THz) surface reflectance maps were acquired of a full thickness skin burn in a rat model to investigate the spatiotemporal evolution of terahertz reflectivity in wound responses. A comparison of uninjured and injured regions in the burn neighborhood demonstrates a 3-fold increase in T2 relaxation times and 15% increase in average THz reflectivity, respectively. These results support the sensitivity and specificity of MRI for measuring burn tissue water content in vivo and the use of this modality to potentially identify THz burn classifiers that best predict tissue viability in future THz studies.

Keywords

biological tissues; biomedical MRI; terahertz wave imaging; wounds; MRI; THz burn wound edema imaging; burn tissue water content; magnetic resonance scans; skin burn; terahertz reflectivity; terahertz surface reflectance maps; Educational institutions; In vivo; Magnetic resonance imaging; Reflectivity; Skin; Wounds;

fLanguage

English

Publisher

ieee

Conference_Titel

Infrared, Millimeter, and Terahertz waves (IRMMW-THz), 2014 39th International Conference on

Conference_Location

Tucson, AZ

Type

conf

DOI

10.1109/IRMMW-THz.2014.6956081

Filename

6956081