Title :
Dielectric Characterization of PCL-Based Thermoplastic Materials for Microwave Diagnostic and Therapeutic Applications
Author :
Aguilar, Suzette M. ; Shea, Jacob D. ; Al-Joumayly, Mudar A. ; Van Veen, Barry D. ; Behdad, Nader ; Hagness, Susan C.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Wisconsin, Madison, WI, USA
fDate :
3/1/2012 12:00:00 AM
Abstract :
We propose the use of a polycaprolactone (PCL)-based thermoplastic mesh as a tissue-immobilization interface for microwave imaging and microwave hyperthermia treatment. An investigation of the dielectric properties of two PCL-based thermoplastic materials in the frequency range of 0.5-3.5 GHz is presented. The frequency-dependent dielectric constant and effective conductivity of the PCL-based thermoplastics are characterized using measurements of microstrip transmission lines fabricated on substrates comprised of the thermoplastic meshes. We also examine the impact of the presence of a PCL-based thermoplastic mesh on microwave breast imaging. We use a numerical test bed comprised of a previously reported 3-D anatomically realistic breast phantom and a multi-frequency microwave inverse scattering algorithm. We demonstrate that the PCL-based thermoplastic material and the assumed biocompatible medium of vegetable oil are sufficiently well matched such that the PCL layer may be neglected by the imaging solution without sacrificing imaging quality. Our results suggest that PCL-based thermoplastics are promising materials as tissue immobilization structures for microwave diagnostic and therapeutic applications.
Keywords :
biomedical imaging; biomedical materials; hyperthermia; microstrip lines; microwave heating; microwave imaging; permittivity; phantoms; polymers; radiation therapy; transmission lines; 3D anatomically realistic breast phantom; PCL layer; PCL-based thermoplastic material; biocompatible medium; dielectric characterization; effective conductivity; frequency 0.5 GHz to 3.5 GHz; frequency-dependent dielectric constant; microstrip transmission line; microwave breast imaging; microwave diagnostic application; microwave hyperthermia treatment; multifrequency microwave inverse scattering algorithm; polycaprolactone-based thermoplastic mesh; therapeutic application; tissue immobilization structure; tissue-immobilization interface; vegetable oil; Breast; Dielectrics; Materials; Microwave imaging; Microwave theory and techniques; Transmission line measurements; Dielectric characterization; microwave hyperthermia; microwave imaging; thermoplastics; tissue immobilization; transmission line measurement; Algorithms; Breast Neoplasms; Diagnostic Imaging; Electric Conductivity; Equipment Design; Female; Humans; Hyperthermia, Induced; Immobilization; Materials Testing; Microwaves; Phantoms, Imaging; Plant Oils; Polyesters; Scattering, Radiation;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2011.2157918