Quantitative analysis of amino acids based on THz refractive index spectra

Author

Han Zhang ; Zhaohui Zhang ; Xiaoyan Zhao ; Zhi Li ; Fang Yan ; Tianyao Zhang

Author_Institution

Univ. of Sci. & Technol. Beijing, Beijing, China

fYear

2014

fDate

14-19 Sept. 2014

Firstpage

1

Lastpage

2

Abstract

The qualitative and quantitative analysis of amino acids by terahertz (THz) refractive index spectra is discussed. The frequency band of anomalous dispersion emerging in the spectra is unique for the amino acids, L-glutamine (Gln) and L-histidine (His). The refractive indices of the amino acids were found to be linearly proportional to the concentrations. The calibration models were established to determine concentrations of Gln and His mixture samples by partial least square (PLS) regression method.

Keywords

biochemistry; calibration; least squares approximations; mixtures; organic compounds; refractive index; regression analysis; terahertz wave spectra; L-glutamine mixture samples; L-histidine mixture samples; amino acids; anomalous dispersion; calibration models; frequency band; partial least square regression method; terahertz refractive index spectra; Amino acids; Dispersion; Materials; Refractive index; Spectroscopy; Statistical analysis; Time-domain analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Infrared, Millimeter, and Terahertz waves (IRMMW-THz), 2014 39th International Conference on

Conference_Location

Tucson, AZ

Type

conf

DOI

10.1109/IRMMW-THz.2014.6956141

Filename

6956141