Title :
Quantitative analysis of amino acids based on THz refractive index spectra
Author :
Han Zhang ; Zhaohui Zhang ; Xiaoyan Zhao ; Zhi Li ; Fang Yan ; Tianyao Zhang
Author_Institution :
Univ. of Sci. & Technol. Beijing, Beijing, China
Abstract :
The qualitative and quantitative analysis of amino acids by terahertz (THz) refractive index spectra is discussed. The frequency band of anomalous dispersion emerging in the spectra is unique for the amino acids, L-glutamine (Gln) and L-histidine (His). The refractive indices of the amino acids were found to be linearly proportional to the concentrations. The calibration models were established to determine concentrations of Gln and His mixture samples by partial least square (PLS) regression method.
Keywords :
biochemistry; calibration; least squares approximations; mixtures; organic compounds; refractive index; regression analysis; terahertz wave spectra; L-glutamine mixture samples; L-histidine mixture samples; amino acids; anomalous dispersion; calibration models; frequency band; partial least square regression method; terahertz refractive index spectra; Amino acids; Dispersion; Materials; Refractive index; Spectroscopy; Statistical analysis; Time-domain analysis;
Conference_Titel :
Infrared, Millimeter, and Terahertz waves (IRMMW-THz), 2014 39th International Conference on
Conference_Location :
Tucson, AZ
DOI :
10.1109/IRMMW-THz.2014.6956141
