Title :
Multi-frequency reference function to reduce noise in functional MRI
Author :
Al-Dayeh, L. ; Kim, T. ; Sungkarat, W. ; Singh, M.
Author_Institution :
Depts. of Radiol. & Biomed. Eng., Univ. of Southern California, Los Angeles, CA, USA
fDate :
6/1/1999 12:00:00 AM
Abstract :
Functional MRI requires acquisition of a time-series of images, making it prone to detecting noise due to gross motion, internal physiological fluctuations, and any magnetic field changes. All of these effects lead to spurious activation, reducing the reliability of functional images. We have designed a unique protocol to present stimuli in fMRI where the presentation sequence contains a combination of frequencies that minimizes the overlap of true activity with noise and any physiological fluctuations, reducing the detection of spurious activation. The results of our studies suggest that the multi-frequency stimuli presentation approach is effective in reducing noise and artifacts
Keywords :
biomedical MRI; correlation methods; image registration; image representation; interference suppression; medical image processing; motion compensation; time series; transient response; artifacts reduction; correlation analysis; functional MRI; gross motion; impulse response; internal physiological fluctuations; magnetic field changes; multi-frequency reference function; multi-frequency stimuli presentation; noise reduction; spurious activation; time-series of images; Biomedical monitoring; Brain; Filters; Fluctuations; Frequency; Magnetic fields; Magnetic noise; Magnetic resonance imaging; Noise reduction; Sampling methods;
Journal_Title :
Nuclear Science, IEEE Transactions on
