Multi-frequency reference function to reduce noise in functional MRI

Author

Al-Dayeh, L. ; Kim, T. ; Sungkarat, W. ; Singh, M.

Author_Institution

Depts. of Radiol. & Biomed. Eng., Univ. of Southern California, Los Angeles, CA, USA

Volume

46

Issue

3

fYear

1999

fDate

6/1/1999 12:00:00 AM

Firstpage

513

Lastpage

519

Abstract

Functional MRI requires acquisition of a time-series of images, making it prone to detecting noise due to gross motion, internal physiological fluctuations, and any magnetic field changes. All of these effects lead to spurious activation, reducing the reliability of functional images. We have designed a unique protocol to present stimuli in fMRI where the presentation sequence contains a combination of frequencies that minimizes the overlap of true activity with noise and any physiological fluctuations, reducing the detection of spurious activation. The results of our studies suggest that the multi-frequency stimuli presentation approach is effective in reducing noise and artifacts

Keywords

biomedical MRI; correlation methods; image registration; image representation; interference suppression; medical image processing; motion compensation; time series; transient response; artifacts reduction; correlation analysis; functional MRI; gross motion; impulse response; internal physiological fluctuations; magnetic field changes; multi-frequency reference function; multi-frequency stimuli presentation; noise reduction; spurious activation; time-series of images; Biomedical monitoring; Brain; Filters; Fluctuations; Frequency; Magnetic fields; Magnetic noise; Magnetic resonance imaging; Noise reduction; Sampling methods;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/23.775572

Filename

775572