• DocumentCode
    1532525
  • Title

    Intrinsic Fluorescence-Based Optical Fiber Sensor for Cocaine Using a Molecularly Imprinted Polymer as the Recognition Element

  • Author

    Nguyen, T. Hien ; Hardwick, Sheila A. ; Sun, Tong ; Grattan, Kenneth T V

  • Author_Institution
    Sch. of Eng. & Math. Sci., City Univ. London, London, UK
  • Volume
    12
  • Issue
    1
  • fYear
    2012
  • Firstpage
    255
  • Lastpage
    260
  • Abstract
    A fiber-optic chemical sensor for the detection of cocaine has been developed, based on a molecularly imprinted polymer (MIP) containing a fluorescein moiety as the signalling group. The fluorescent MIP was formed and covalently attached to the distal end of an optical fiber. The sensor exhibited an increase in fluorescence intensity in response to cocaine in the concentration range of 0 - 500 μM in aqueous acetonitrile mixtures with good reproducibility over one month. Selectivity for cocaine over others drugs has also been demonstrated.
  • Keywords
    chemical sensors; fibre optic sensors; cocaine; fiber-optic chemical sensor; fluorescein moiety; intrinsic fluorescence-based optical fiber sensor; molecularly imprinted polymer; recognition element; signalling group; Drugs; Fluorescence; Optical fiber sensors; Polymers; Probes; Water; Cocaine sensor; fluorescein; fluorescent sensor; molecular imprinting; optical fiber sensor;
  • fLanguage
    English
  • Journal_Title
    Sensors Journal, IEEE
  • Publisher
    ieee
  • ISSN
    1530-437X
  • Type

    jour

  • DOI
    10.1109/JSEN.2011.2158537
  • Filename
    5783499